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KMID : 0357520220450030241
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Journal of Radiological Science and Technology
2022 Volume.45 No. 3 p.241 ~ p.248
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Comparison of Recovery Coefficients for Correction of Reduced SUV by Partial Volume Effect and Organ Movements in PET/CT Images
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Kim Young-Jae
Park Hoon-Hee
Lee Joo-Young
So Young
Lee Jeong-Woo
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Abstract
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In this study, a recovery coefficient (RC) calculation was conducted that can correct the underestimation of the standardized uptake value (SUV) due to the partial volume effect (PVE) through phantom measurements and formulas.
The experiment was conducted using a dynamic phantom capable of implement cranio-caudal movement at a respiratory rate of 15 times per minute along with the measured phantom experiment of the stopped state, and the RC of the moving state is calculated and compared. Ingenuity TF (Philips Healthcare, Netherland) was used as a positron emission tomography/ computed tomography (PET/CT) device. PET-CT Phantom (Biodex Medical System, USA) was used as a phantom for measurement. A phantom image in a stationary state was acquired, and a moving phantom image was acquired using the AZ-733V Respiratory Phantom (Anzai Medical Co, Japan) capable of breathing movement in the cranio-caudal direction under the same acquisition parameters. For RC calculation, the sphere maximum radioactivity concentration and the background mean radioactivity concentration of the acquired images were measured, and the initially determined sphere and background radioactivity concentrations were calculated. The calculated RC was 0.08 to 0.72. The size of sphere smaller, it was confirmed that the RC reduced. And the RC in the moving state reduced than in the stationary state. As a result of this study, the change of the RC was confirmed according to the size of spheres and the phantom moving. Using the RC derived by implement movement of breathing with the respiratory phantom, it is possible to considering correction of underestimated SUV by the partial volume effect of PET images and the patient movements.
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KEYWORD
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PET/CT, Standardized Uptake Value, Partial Volume Effect, Recovery Coefficient, Partial Volume Correction, Respiration
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